Study of Physiological and Biochemical Changes in Rabbit Blood: Resulting from Exposure to Wavelengths (565,810,1064) nm Used in Home Cosmetic Lasers

Abstract

Abstract:  This study aimed to evaluate the physiological and biochemical effects of the home laser technology (Intense Pulsed Light - IPL), designed for hair removal in various body areas, using three wavelengths (565, 810, 1064) nm on the skin and surrounding areas. Twenty-four female domestic rabbits were used, randomly divided into four groups: Group 1 (control), Group 2 (exposed to the 565 nm wavelength), Group 3 (exposed to the 810 nm wavelength), and Group 4 (exposed to the 1064 nm wavelength). The measurements used in this study were for two time periods: 3 and 6 weeks. The study focused on assessing changes in vital and hematological indicators resulting from repeated exposure to radiation. Blood analysis results revealed changes in some blood components and characteristics. The results revealed significant physiological effects associated with the length of exposure and wavelength. Analyses also revealed statistically significant differences (P≤0.05) in the studied parameters. These changes included a decrease in the number of white and red blood cells, along with changes in other hematological indicators such as HGB, LYM%, and changes in biochemical indicators such as GOT (AST), LDH, ALP, and CRP. These results indicate that home laser radiation has potential physiological effects on blood components and vital functions. These effects depend primarily on the wavelength used and the duration of exposure, highlighting the need for further studies to further understand the mechanisms of these biological effects.